Nasal insulin study aims to uncover Obesity's hidden effects on brain and blood flow
NCT ID NCT07653464
First seen Jun 19, 2026 · Last updated Jun 19, 2026
Summary
This early-phase study will test how insulin given as a nasal spray affects nerve activity and blood flow in the brain and legs. Researchers will compare 64 adults with obesity and insulin resistance to healthy-weight individuals. The goal is to understand how obesity changes the body's response to insulin beyond blood sugar control.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Missouri
Columbia, Missouri, 65211, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
human insulin (given as a nasal spray)
What this could lead to
If successful, this study could reveal how obesity-related insulin resistance alters brain and blood vessel responses, pointing toward new ways to manage metabolic health.
What could go wrong
This is a very early, small study (64 people) that only measures short-term nerve and blood flow changes, not health outcomes. It may not lead to any treatment.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.