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Can a Live-Streaming brain health program boost memory in older adults?

NCT ID NCT05818423

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a 12-week online program called Brain Health Together for older adults with mild cognitive decline. Participants joined live-streaming exercise and education classes, plus individual coaching, all from home. The goal was to see if the program could improve thinking skills and reduce dementia risk factors. The study enrolled 208 people across the U.S. and measured changes in cognitive performance and risk scores at 3 and 6 months.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Brain Health Together program (online group classes, coaching, and education)
What this could lead to
If it works, this could offer a practical, home-based way to help older adults with mild memory problems stay mentally sharp and lower their dementia risk.
What could go wrong
This is a small, completed study without a clear phase, so results are preliminary. The program may not work for everyone, and long-term benefits are unknown.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

208 people

The number who actually took part.

Started

Apr 2023

Finished

Nov 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

55 to 85 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * English language fluency;\* * live in U.S.; * cognitive decline (subjective cognitive decline OR diagnosis of mild cognitive impairment in the past 12 months) * ready to make lifestyle changes to improve brain health; * have 2 or more brain health risk factors (e.g., low physical activity, depression, hypertension, diabetes, etc) * have a desktop or laptop computer or iPad/tablet with a video camera; * have broadband internet access; * able to participate in online, live-streaming classes with two-way video Exclusion Criteria: Candidates meeting any of the exclusion criteria will not be eligible to participate. Alzheimer's disease or dementia \- Major neurological disorder (e.g., Parkinson's disease, Multiple Sclerosis, amyotrophic Lateral Sclerosis) * Schizophrenia or other psychotic disorder * Autism or autism spectrum disorder * Major mood or anxiety disorder that is not well-controlled (e.g., symptoms of depression or anxiety that made it hard to do daily tasks in past 6 months) * Fracture of spine ("compression fracture") in the past 12 months * Vertigo or severe dizziness in the past 12 months * Severe vision or hearing impairment (e.g., unable to see and hear well enough to watch a movie on TV); * Stroke or heart attack in the past 12 months * Physical limitation that would restrict ability to participate (e.g., use wheelchair or walker to get around home, unable to stand up from sitting without assistance) * Currently in another research study that could confound results of this study (e.g., drug study or other study to improve brain health) * Previous participation in Moving Together or Brain Health Together * Limited life expectancy (e.g., enrolled in hospice, undergoing cancer treatment) If participants are not sure about certain conditions, they will be asked to describe their condition, and the research team will determine whether they meet eligibility criteria or not.

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Conditions

The condition(s) this trial relates to.

Cognition Disorders Cognitive Dysfunction follicular lymphoma subjective cognitive decline

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of California, San Francisco

    San Francisco, California, 94143, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.