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Teen Self-Harm study uses brain scans to uncover clues

NCT ID NCT02947308

Knowledge-focused Sponsor: University of Minnesota Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how the brain develops over time in young teenage girls who have hurt themselves on purpose (non-suicidal self-injury). Researchers used interviews, brain scans (MRI), and thinking tests to understand the condition better. A total of 168 girls took part, including some who had self-harmed and some who had not, to compare their brain changes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

168 people

The number who actually took part.

Started

Aug 2016

Finished

Jul 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adolescents with a history of NSSI will be recruited from community outlets such as flyers, as well as through social media (e.g., Facebook and Pandora). Additionally, these adolescents will be recruited through local clinicians who treat adolescent mood disorders. Healthy controls will be recruited through community outlets and social media.

Ages

12 to 16 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 12-16 years old * Female * Has had first menstruation * Willingness to have de-identified data shared with RDoC database Inclusion Criteria - Adolescents with Non-Suicidal Self-Injury: * Any history of self harm Inclusion Criteria - Healthy Controls: * No history of self harm Exclusion Criteria: * Male * Pregnancy * MRI Incompatibility * IQ of less than 80 * Major Medical Illness * Diagnosis of any of the following: Primary Psychotic Disorder, Bipolar Spectrum Disorder, Autism Spectrum Disorder, Current or Past Substance Use Disorder

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Conditions

The condition(s) this trial relates to.

anxiety disorder Depression Self-Injurious Behavior

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Deliberate self-harm Self-injurious behavior

Contacts and locations

Locations

  • Ambulatory Research Center (ARC)

    Minneapolis, Minnesota, 55454, United States

  • Center for Magnetic Resonance Research

    Minneapolis, Minnesota, 55455, United States

  • University of Minnesota

    Minneapolis, Minnesota, 55455, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.