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Can botox make biopsy scars disappear?

NCT ID NCT05478551

Symptom relief Sponsor: Henry Ford Health System Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether injecting botulinum toxin (Botox) into biopsy wounds can reduce scarring compared to a placebo. Twelve healthy adults will each receive both treatments on different spots on their back, and scars will be compared over six months. The goal is to see if Botox can help wounds heal with less visible scarring.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
botulinum toxin (Dysport)
What this could lead to
If it works, this could offer a simple way to minimize scars from skin biopsies.
What could go wrong
This is a very small early-phase trial with only 12 participants, so results may not apply widely. The treatment is for cosmetic improvement, not a cure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2/3

Runs two stages together: whether the treatment works, then large-scale confirmation.

Participants

12 people

The number who actually took part.

Started

Jun 2022

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Healthy Individuals age 18 and older * Able to understand the requirements of the study and its associated risks * Able to complete and sign a consent form Exclusion Criteria: * Allergy to botulinum toxin * Currently pregnant or breastfeeding * Myasthenia gravis * Previous injection of botulinum toxin in the specified treatment areas within 6 months prior to enrollment * Unable to follow up 6 months after biopsy procedure * Refusal to participate in the trial * History of keloid or hypertrophic scars * Eaton-Lambert Syndrome * Amyopathic Lateral Sclerosis

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Conditions

The condition(s) this trial relates to.

Cicatrix, Hypertrophic severe cutaneous adverse reaction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hypertrophic scar Scar

Contacts and locations

Locations

  • Henry Ford Health System

    Detroit, Michigan, 48202, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.