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New study aims to help HIV patients in botswana kick the habit

NCT ID NCT05694637

First seen Jan 11, 2026 · Last updated Jun 23, 2026 · Updated 24 times

Summary

This study tests a program to help people living with HIV in Botswana stop smoking. It combines counseling with a medication called varenicline. The goal is to see if this approach helps them quit and improves their health. The study involves 750 participants who are daily smokers and on HIV treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Airstrip Clinic

    Mahalapye, Central District, Botswana

  • Goodhope Primary Hospital

    Good Hope, Botswana

  • Itekeng Clinic

    Francistown, Central District, Botswana

  • Kanye Adventist Hospital

    Kanye, Botswana

  • Kediretswe Clinic

    Palapye, Botswana

  • Mahalapye District Hospital

    Mahalapye, Central District, Botswana

  • Masego Clinic

    Francistown, Central District, Botswana

  • Morwa Clinic

    Mochudi, Central District, Botswana

  • Nyangabgwe Referral Hospital

    Francistown, Central District, Botswana

  • Palpye Primary Hospital

    Palapye, Central District, Botswana

  • Sefhare Primary Hospital

    Sefhare, Central District, Botswana

  • Sekgoma District Hospital

    Serowe, Botswana

  • Serowe Clinic

    Serowe, Botswana

  • Thamaga Primary Hospital

    Thamaga, Kweneng District, Botswana

  • Tutume Primary Hospital

    Tutume, Central District, Botswana

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

varenicline

What this could lead to

If successful, this could provide an effective, scalable way to help people with HIV quit smoking, reducing HIV complications and deaths.

What could go wrong

This is a phase 4 trial, but results may not apply to all populations. Adherence to medication and counseling can be challenging, and the intervention may not work for everyone.

Conditions

The condition(s) this trial relates to.

AIDS HIV infectious disease nicotine dependence Smoking Cessation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.