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Scientists use ultrasound to peek inside bones for space health

NCT ID NCT06206031

Knowledge-focused Sponsor: University Hospital, Angers Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a new ultrasound technique to measure blood flow inside the shin bone of 30 healthy men. Researchers used simple exercises and pressure cuffs to see how bone blood vessels react. The goal is to develop a tool that could one day help monitor bone health in astronauts during space travel.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this method could help monitor bone health in astronauts during space missions.
What could go wrong
This is a small, early pilot study in healthy volunteers, so results may not apply to patients or real-world conditions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

30 people

The number who actually took part.

Started

Mar 2024

Finished

Oct 2024

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 70 years

Sex

Male participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria for sub-protocol 1: * Male aged 20-40 years Inclusion criteria for sub-protocol 2: * Male aged 20-40 years \& 50-70 years * Body height of at least 180 cm (in order to have tibia length of 43-45 cm allowing the positioning of ultrasonic probe at distal tibia, and occlusive cuff at calf level) * Bone densitometry with available report performed within 5 last years (if none has been done, possibility to perform densitometry covered by the study at selection or inclusion visit) Inclusion criteria common for both sub-protocols: * Healthy volunteer without chronic pathology (in particular no known rhythm disorder) or long-term treatment * No symptomatic acute medical event requiring treatment on the visit days * No history of tibia fractures * Body Mass Index between 19 and 26 * Affiliation to the French Social Security System * Written informed consent Non-Inclusion criteria: * Inability to stay still for 20 minutes (tremor) * Active smoking (stopped less than 1 year ago) * History of prolonged corticosteroid treatment * Deprivation of liberty by legal or administrative decision * Subject to involuntary psychiatric treatment * Subject to a legal protection measure * For sub-study 1: Osteoporosis known at interview Exclusion Criteria: * Any abnormality or deviation from the selection criteria identified during the clinical examination at the inclusion visit (non-sinus rhythm in ECG, body temperature \> 38°C, blood pressure or heart rate outside the defined standards, etc.)

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Conditions

The condition(s) this trial relates to.

Arterial Occlusive Diseases

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Healthy volunteers

Contacts and locations

Locations

  • CHU d'Angers

    Angers, 49933, France

  • CHU de Saint-Etienne

    Saint-Etienne, 42055, France

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