New MRI dye may reveal hidden epilepsy hotspots in the brain

NCT ID NCT02531880

Recruiting now Knowledge-focused Sponsor: National Institute of Neurological Disorders and Stroke (NINDS) Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 22, 2026 · Updated 31 times

Summary

This study is testing whether a special MRI dye called mangafodipir is safe and can better show areas of the brain affected by epilepsy in people whose seizures are not controlled by medication. About 40 adults aged 18-60 with drug-resistant epilepsy will receive the dye and have several MRI scans over a few weeks. The goal is to see if this dye can help doctors identify where seizures start, which could improve future treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

National Institutes of Health Clinical Center
RECRUITING

Bethesda, Maryland, 20892, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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EPILEPSY