New MRI dye may reveal hidden brain barrier damage in epilepsy patients

NCT ID NCT02531880

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 28 times

Summary

This study is testing whether a special MRI dye called mangafodipir is safe and can show areas where the blood-brain barrier is broken in people with epilepsy that doesn't get better with medication. About 40 adults aged 18-60 will get the dye and have several MRI scans over a few weeks. The goal is to see if this method can help find the exact spot in the brain where seizures start.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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