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Blood test could help paramedics spot severe strokes before the hospital

NCT ID NCT04726839

Diagnosis Sponsor: Assistance Publique - Hôpitaux de Paris Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study looked at whether a panel of blood biomarkers can quickly identify stroke patients who have a large vessel occlusion (a major blockage) and would benefit from a specialized clot-removal procedure. Researchers enrolled nearly 3,900 adults with stroke symptoms and tested their blood in the ambulance or emergency room. The goal is to help paramedics decide which hospital to take a patient to, avoiding delays that can worsen outcomes.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
blood biomarker panel
What this could lead to
If successful, this blood test could help paramedics quickly identify stroke patients who need a specialized clot-removal procedure, getting them to the right hospital faster and improving outcomes.
What could go wrong
This is a completed study analyzing blood samples, not a treatment trial. The biomarker panel may not be accurate enough in real-world ambulance settings, and further validation is needed before it can be used routinely.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

3,880 people

The number who actually took part.

Started

Mar 2021

Finished

Jul 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients with stroke suspicion within 24 hours of stroke's symptoms

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Symptoms consistent with stroke \<24 hours * Adult patients ≥ 18 years old * Non opposition of the patient or his/her relatives to the research (emergency inclusion procedure) Exclusion Criteria: * Patient under guardianship or curatorship

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Conditions

The condition(s) this trial relates to.

cerebral artery occlusion ischemic stroke large artery stroke

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Large vessel occlusion Stroke, ischemic

Contacts and locations

Locations

  • Department Neurology Caen Hospital

    Caen, France

  • Hospital Foch

    Suresnes, France

  • Lariboisière

    Paris, 75010, France

  • Rothschild Foundation Hospital

    Paris, France

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