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New biomaterial may keep jawbone strong after losing multiple teeth

NCT ID NCT02903667

Disease control Sponsor: Institute Franci Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a collagen-based material placed into fresh tooth sockets after extraction can reduce bone shrinkage. Forty adults with multiple teeth removed received the material and later dental implants. The goal was to see if the treatment preserves jawbone shape and density over six months to three years, helping maintain a good foundation for implants.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

40 people

The number who actually took part.

Started

Mar 2015

Finished

Sep 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

25 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria:intact extraction sockets following removal of the natural teeth defined by: * a marginal dehiscence defect of any of the facial bone walls of 3 mm * no facial fenestration present in the apical of the marginal bone crest Exclusion Criteria: * untreated rampant caries and uncontrolled periodontal disease * uncontrolled diabetes or any other systemic or local disease or condition that would compromise post-operative healing * unable or unwilling to return for follow-up or unlikely to be able to comply with study procedures according to investigators judgement.

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Conditions

The condition(s) this trial relates to.

bone resorption disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Alveolar ridge trauma Bone resorption

Contacts and locations

Locations

  • Franci Institute

    Padova, 35121, Italy

More trials for these conditions

Other studies related to the condition(s) this trial covers.