Could a cancer drug beat steroids for brain radiation injury?
NCT ID NCT06888817
First seen Jan 04, 2026 · Last updated May 21, 2026 · Updated 17 times
Summary
This study compares bevacizumab, a drug that blocks blood vessel growth, to standard steroid treatment for people with brain damage from radiation therapy. About 408 adults with brain tumors or high-grade glioma who develop symptomatic radiation necrosis will be randomly assigned to one of the two treatments. The goal is to see which approach better improves daily function and quality of life while reducing the need for long-term steroids.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Amsterdam University Medical Centers, location VUmc and AMC
RECRUITINGAmsterdam, Netherlands
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Haaglanden Medical Center
RECRUITINGThe Hague, 2262 BA Leidschendam, Netherlands
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Leiden University Medical Center
RECRUITINGLeiden, 2333 ZA Leiden, Netherlands
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Netherlands Cancer Institute - Antoni van Leeuwenhoek
RECRUITINGAmsterdam, 1066 CX Amsterdam, Netherlands
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University Medical Center Utrecht
RECRUITINGUtrecht, 3584 CX Utrecht, Netherlands
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