Can a heart drug curb cigarette cravings? scientists scan smokers' brains to find out.

NCT ID NCT05587361

Recruiting now Knowledge-focused Sponsor: University of Oklahoma Source: ClinicalTrials.gov ↗

First seen Apr 30, 2026 · Last updated May 23, 2026 · Updated 7 times

Summary

This study looks at how a beta-blocker (propranolol) and nicotine patches, alone or together, affect smokers' brain activity and cravings when they see smoking-related cues. About 80 daily smokers will have MRI scans and rate their urges. Participants do not try to quit or take the medications long-term. The goal is to understand the brain mechanisms behind smoking triggers, not to treat addiction.

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Contacts and locations

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Study contacts

Contact

Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Hardesty Center for Clinical Research and Neuroscience
RECRUITING

Tulsa, Oklahoma, 74136, United States

Contact Email: •••••@•••••

Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.

CIGARETTE SMOKING CIGARETTE SMOKING NICOTINE DEPENDENCE TOBACCO USE DISORDER