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Beetroot extract shows promise for heart and sleep health in Middle-Aged adults

NCT ID NCT06117007

Symptom relief Sponsor: King's College London Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a daily capsule of betalains from red beetroot can improve blood vessel function, sleep, and quality of life in healthy adults aged 40 to 65. Forty-two participants took either the betalain supplement or a placebo for one month, then switched. Researchers measured blood vessel flexibility, blood pressure, and sleep using a fitness tracker and questionnaires.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
betalains from red beetroot
What this could lead to
If it works, this could point toward a natural supplement to support heart health and sleep in middle-aged people.
What could go wrong
This is a small, early-stage trial with only 42 participants. The effects may be small or not noticeable, and results may not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

42 people

The number who actually took part.

Started

Oct 2023

Finished

Dec 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Aged between 40 and 65 years * BMI between 25-29.9 kg/m2 * Own a smartphone. * Able to understand the nature of the study and give informed consent * Have not gained or lost more than 10% of body weight (within the past 3 months) * Not currently involved or have participated in another biomedical study (within the last 3 months) Exclusion Criteria: * Smoking or vaping (within the last 2 years) * Vegetarian or vegan (due to capsule material) * Medical history of chronic disease \[coronary artery disease, previous myocardial infarction (heart attack), stroke, peripheral artery disease, diabetes mellitus, chronic kidney disease, metabolic syndrome, malignancies, etc\] * Grade II hypertension (blood pressure: \>160/100 mmHg) * Under medication that can affect the cardiovascular system (within the last 2 months) * Taking supplements (except vitamin D and iron) (within the last month) * Intolerances or allergies toward beetroots, dragon fruit or rice hulls * History of excess alcohol intake or substance abuse. * Pregnant or planning to become pregnant in the next 6 months * Under hormonal replacement therapy (contraceptives are allowed)

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Conditions

The condition(s) this trial relates to.

Aneurysm sleep disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Quality of life Sleep Vascular stiffness Vasodilation

Contacts and locations

Locations

  • Metabolic Research Unit (King's College London)

    London, London, SE1 9NH, United Kingdom

More trials for these conditions

Other studies related to the condition(s) this trial covers.