Sound waves help chemo reach brain tumors in early trial
NCT ID NCT04998864
First seen Jan 04, 2026 · Last updated Jun 18, 2026 · Updated 26 times
Summary
This small study tested whether a device using focused ultrasound can safely open the blood-brain barrier in patients with high-grade glioma (a type of aggressive brain cancer). The goal was to allow standard chemotherapy to reach the tumor more effectively. Only 3 patients were enrolled, and the study focused on safety and whether the barrier could be opened repeatedly. This is not a cure, but a way to improve existing treatment.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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CINAC-Hospital HM Puerta del Sur
Móstoles, Madrid, 28938, Spain
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Fondazione IRCCS Neurologico Carlo Besta
Milan, 20133, Italy
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.