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Electric pulses and video games could help spinal cord injury patients stay on their feet

NCT ID NCT05940636

Disease control Sponsor: University Health Network, Toronto Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a new therapy that combines two types of electrical stimulation with balance training (like video games) to help people with incomplete spinal cord injury improve their standing balance. Seventeen participants completed 12 sessions over 4 weeks. The goal was to see if the combined stimulation could strengthen brain-to-muscle connections and reduce fall risk.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
electrical stimulation (functional electrical stimulation and transcutaneous spinal cord stimulation)
What this could lead to
If it works, this could lead to a new therapy that improves balance and reduces falls for people with incomplete spinal cord injury.
What could go wrong
This is a small, early study with only 17 participants, so results may not apply to everyone. The therapy is experimental and may not provide lasting benefits.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

17 people

The number who actually took part.

Started

Nov 2023

Finished

Jan 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. A traumatic or non-traumatic, non-progressive motor iSCI \[American Spinal Injury Association Impairment Scale (AIS) rating of C or D\]; 2. More than 1-year post-injury; 3. ≥18 years old; 4. BBS score \<46; 5. Free of any other condition besides SCI that significantly affects walking or balance (e.g., no vestibular disorder, significant vision loss, stroke) Exclusion Criteria: 1. Neurological lesion levels below T12 ; 2. Severe spasticity in the legs; 3. Contractures in the lower extremities that prevent achieving a neutral hip and ankle position, or extended knee; 4. Peripheral nerve damage in the legs (i.e. leg muscles unresponsive to electrical stimulation); 5. A pressure sore (\>grade 2) on the pelvis or trunk where the safety harness is applied; 6. Pregnancy; 7. History of epilepsy; 8. Contraindications for electrical stimulation (i.e. implanted electronic device, active cancer or radiation in past months, epilepsy, skin rash/wound at a potential electrode site)

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Conditions

The condition(s) this trial relates to.

Paresis spinal cord injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

FALL Muscle pareses Spinal cord injuries

Contacts and locations

Locations

  • Toronto Rehabilitation Institute-Lyndhurst Center

    Toronto, Ontario, m4g3v9, Canada

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