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New cell therapy combo targets tough childhood cancers

NCT ID NCT07222735

First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 25 times

Summary

This early-stage study tests whether a new treatment combining radiation and specially engineered immune cells (B7-H3-CAR T cells) is safe for children and young adults up to age 21 with sarcomas that have returned or not responded to standard therapy. The treatment aims to help the immune system better attack the cancer. About 42 participants will be enrolled to assess safety and see if the therapy shows signs of shrinking tumors.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • St. Jude Children's Research Hospital

    RECRUITING

    Memphis, Tennessee, 38105, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.