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New drug-radiation combo tested for deadly brain lining cancer

NCT ID NCT06724926

First seen Jan 10, 2026 · Last updated May 23, 2026 · Updated 14 times

Summary

This early-phase study tests the safety of adding the drug azeliragon to radiation therapy for adults whose cancer has spread to the lining of the brain and spinal cord (leptomeningeal metastasis). About 21 participants with solid tumors or high-grade gliomas will receive the combination. The main goal is to identify any severe side effects, while also tracking how long the cancer stays controlled in the central nervous system and overall survival.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • NYU Langone Health

    New York, New York, 10016, United States

Conditions

Explore the condition pages connected to this study.