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Weight-Loss injections may alter contraception effectiveness

NCT ID NCT07013643

First seen Nov 06, 2025 · Last updated Jun 22, 2026 · Updated 33 times

Summary

This early-stage study in 50 healthy women with overweight or obesity examines whether two experimental weight-loss injections, AZD6234 and AZD9550, change how the body processes a common birth control pill. Participants will receive the drugs alone and together, and researchers will measure hormone levels in the blood. The goal is to ensure women using these future treatments can still rely on oral contraception.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Research Site

    RECRUITING

    Glendale, California, 91206, United States

  • Research Site

    RECRUITING

    Brooklyn, Maryland, 21225, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

AZD6234 and AZD9550 (injectable drugs for weight loss)

What this could lead to

If successful, this study will show whether these weight-loss drugs change how birth control pills work, helping women choose effective contraception.

What could go wrong

This is an early Phase 1 trial with only 50 healthy participants, so results may not apply to everyone. The study focuses on drug interactions, not on treating a disease.

Conditions

The condition(s) this trial relates to.

Obesity Overweight

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.