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New drug combo targets deadly brain tumors in first human trial

NCT ID NCT03423628

First seen Nov 01, 2025 · Last updated May 20, 2026 · Updated 29 times

Summary

This study tests a new drug called AZD1390 given together with radiation therapy for people with glioblastoma (a fast-growing brain cancer) or brain tumors that have spread from other cancers. It is the first time this drug is used in humans, so the main goals are to find safe doses and understand side effects. About 180 adults with these brain tumors will take part across multiple centers.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Research Site

    RECRUITING

    Boston, Massachusetts, 02114, United States

  • Research Site

    RECRUITING

    Boston, Massachusetts, 02215, United States

  • Research Site

    RECRUITING

    New York, New York, 10065, United States

  • Research Site

    RECRUITING

    Pittsburgh, Pennsylvania, 15232, United States

  • Research Site

    RECRUITING

    Richmond, Virginia, 23298, United States

  • Research Site

    COMPLETED

    Chūōku, 104-0045, Japan

  • Research Site

    ACTIVE_NOT_RECRUITING

    Hidaka-shi, 350-1298, Japan

  • Research Site

    ACTIVE_NOT_RECRUITING

    Kyoto, 606-8507, Japan

  • Research Site

    ACTIVE_NOT_RECRUITING

    Cambridge, CB2 0QQ, United Kingdom

  • Research Site

    COMPLETED

    Glasgow, G12 0YN, United Kingdom

  • Research Site

    RECRUITING

    Leeds, LS9 7TF, United Kingdom

  • Research Site

    WITHDRAWN

    London, W1T 7HA, United Kingdom

Conditions

Explore the condition pages connected to this study.