New alert system aims to stop Post-Surgery nausea in its tracks
NCT ID NCT07152249
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new computer alert system that reminds doctors to give the right anti-nausea medicines at the right time during surgery. About 19,480 adults having planned surgery will take part. The goal is to see if these smart reminders can reduce how many people feel sick or vomit after waking up from anesthesia.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 19,480 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2025
- Expected to finish
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Sep 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Adult Inclusion Criteria * Age ≥ 18 years * Planned surgery with general anesthesia with endotracheal intubation or laryngeal mask airway * Meet zero or more risk factors for PONV ( history of motion sickness or postoperative nausea and vomiting, non-smoker, female sex, duration of inhalation anesthesia greater than 1 hour, undergoing high risk surgical procedure (cholecystectomy, laparoscopy, gynecologic), and perioperative opioid use) Adult Exclusion Criteria * ASA 6 including organ procurement, * Patients anticipated to be transferred directly to the intensive care unit intubated, * Procedure types: * Electroconvulsive therapy, * Intubation only cases, * labor epidurals, * transesophageal echocardiography (TEE)/cardioversion, * surgery duration \< 30 minutes. Operating Room Anaesthesia Provider Inclusion Criteria Any operating room anaesthesia provider of eligible patients will be included.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Vanderbilt University Medical Center
RECRUITINGNashville, Tennessee, 37212, United States
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