Which steroid helps kids wake up faster after surgery?
NCT ID NCT07175623
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at how two common steroids, methylprednisolone and dexamethasone, affect the time it takes for children to recover from muscle relaxants used during surgery. Sixty children aged 5 to 12 received one of the steroids or a placebo before their operation. The goal was to see which steroid helps reverse the muscle relaxant fastest and reduces pain and nausea afterward.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- methylprednisolone and dexamethasone (steroids)
- What this could lead to
- If successful, this could help anesthesiologists choose the best steroid to speed recovery from muscle relaxants in children, reducing side effects like pain and nausea.
- What could go wrong
- This is a small, completed trial with only 60 children. Results may not apply to all ages or surgeries, and the exact impact on recovery time is still uncertain.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
60 people
The number who actually took part.
- Started
-
Sep 2025
- Finished
-
Dec 2025
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
5 to 12 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Children aged 5-12 years * American Society of Anesthesiologists (ASA) physical status I-II Exclusion Criteria: * ASA physical status ≥ III * Emergency surgery * Known allergy or contraindication to neuromuscular blocking agents, sugammadex, or corticosteroids * Chronic or recent systemic corticosteroid use (within the last 3 months) * Neuromuscular disorders (e.g., muscular dystrophy, myasthenia gravis) * Severe hepatic or renal dysfunction * Significant respiratory or cardiac disease * Anticipated difficult airway or history of difficult intubation * Developmental delay or craniofacial anomalies affecting airway management * Refusal of consent
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Bezmialem Vakıf Univerisity Dragos Hospital
Istanbul, Turkey (Türkiye)
-
Konya City Hospital
Konya, Karatay, 42050, Turkey (Türkiye)
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