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Which steroid works best with sugammadex? new study aims to find out

NCT ID NCT07187037

Knowledge-focused Sponsor: Konya City Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study compares two common steroids—methylprednisolone and dexamethasone—given during nose surgery to see how they affect how quickly the muscle relaxant rocuronium is reversed by sugammadex. Researchers will measure reversal time, pain, nausea, and other recovery outcomes in 130 adults. The goal is to provide better guidance for anesthesiologists on which steroid to use for smoother recovery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
methylprednisolone and dexamethasone (corticosteroids)
What this could lead to
If it works, this could help anesthesiologists choose the best steroid to speed up recovery from muscle relaxants and reduce side effects after surgery.
What could go wrong
This is a small, early-stage study (130 patients) looking at timing and side effects, not a cure or major treatment. Results may not apply to other surgeries or patient groups.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 130 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Oct 2025

An estimate. Start dates often move.

Expected to finish

Apr 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult patients aged 18-65 years * American Society of Anesthesiologists (ASA) physical status I-II * Scheduled for elective septoplasty or rhinoplasty under general anesthesia * Written informed consent obtained Exclusion Criteria: * ASA physical status ≥ III * Emergency surgery * Known allergy or contraindication to rocuronium, sugammadex, or corticosteroids * Chronic or recent (within 3 months) systemic corticosteroid therapy * Concomitant use of drugs that may interact with sugammadex (e.g., toremifene, flucloxacillin, fusidic acid) * Neuromuscular disorders (e.g., myasthenia gravis, muscular dystrophy) * Significant hepatic, renal, respiratory, or cardiac dysfunction * Anticipated difficult airway or history of difficult intubation * Nasopharyngeal or oropharyngeal anomalies interfering with airway management * Developmental or cognitive impairment interfering with informed consent or cooperation

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Conditions

The condition(s) this trial relates to.

Delayed Emergence from Anesthesia Pain Pain, Postoperative Postoperative Nausea and Vomiting

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Neuromuscular block, residual Pain Postoperative nausea

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Konya City Hospital

    Karatay, Konya, 42050, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.