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Can removing colon tissue through the anus prevent hernias? new study aims to find out.

NCT ID NCT07615036

Knowledge-focused Sponsor: Singapore General Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tracks 800 adults across Asia-Pacific who need minimally invasive colorectal surgery. Half will have the removed tissue taken out through a natural opening (anus or vagina), the other half through a small cut in the belly. Researchers will compare how many develop hernias at the extraction site within two years, along with infection rates and recovery. The study does not assign treatment—it simply observes what happens in routine care.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could show that removing surgical specimens through a natural orifice reduces hernia risk and speeds recovery after colorectal surgery.
What could go wrong
This is an observational registry, not a randomized trial, so results may be influenced by patient selection. It is also limited to the Asia-Pacific region, so findings may not apply worldwide.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 800 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2026

Expected to finish

Dec 2033

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients undergoing elective minimally invasive colorectal resection with planned intact specimen extraction at participating tertiary colorectal centers in the Asia-Pacific region.

Ages

21 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 21 years or older * Elective minimally invasive colorectal resection (laparoscopic or robotic intent) * Planned intact specimen extraction * Eligible for natural orifice specimen extraction (NOSE) or transabdominal specimen extraction according to study protocol * Ability to provide informed consent Exclusion Criteria: * Emergency colorectal surgery * Planned transanal total mesorectal excision (TaTME) * Planned ultralow anterior resection with planned anastomosis 3 cm or less from the anal verge * Planned abdominoperineal resection (APR) * Planned permanent end stoma without restoration of intestinal continuity * Planned multivisceral resection * Generalized peritonitis or uncontrolled intra-abdominal sepsis * Pregnancy * Pre-existing ventral or incisional hernia at the planned extraction site * Planned specimen extraction through a prior laparotomy incision containing mesh * Fixed distal obstruction, severe pelvic stenosis, or other anatomical constraint precluding intact specimen extraction

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Conditions

The condition(s) this trial relates to.

colorectal neoplasm Incisional Hernia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Colorectal neoplasms Incisional hernia

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Singapore General Hospital

    RECRUITING

    Singapore, 169608, Singapore

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