Collagen pills promising sharper memory for Stressed-Out workers
NCT ID NCT07572240
First seen Jun 27, 2026 · Last updated Sep 21, 2026 · Updated 7 times
Summary
This study tests whether a daily collagen supplement called AP-Brain can improve attention, focus, and memory in adults aged 35-70 who are stressed but otherwise healthy. Seventy-two participants will take either a higher or lower dose for 56 days and complete memory tasks and stress surveys. Researchers will also monitor brain activity and side effects to see if the supplement makes a real difference.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- AP-Brain collagen peptides (dietary supplement)
- What this could lead to
- If it works, this could point toward a natural supplement to help stressed adults sharpen focus and memory.
- What could go wrong
- This is a small, early proof-of-concept study with no placebo group, so results may be weak or biased. It only tests short-term effects in healthy people, not a treatment for any disease.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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72 people
The number who actually took part.
- Started
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Jul 2026
- Expected to finish
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Nov 2026
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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35 to 70 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Individuals ready to give voluntary, written informed consent to participate in the study. * Male and female individuals of age between 35 to 70 years (both values included). * Individuals with body mass index (BMI) between 18.5 kg/m\^2 to 29.9 kg/m\^2 (both values included). * Perceived Stress Scale (PSS) scores between 14 to 26 (both values included). * Individuals with mild cognitive impairment as indicated by Addenbrooke's Cognitive Examination (ACE) III scores between 75 to 88 (both values included). * Self-reported mild difficulties in focus, attention, or memory. * Progressive cognitive complaints like stress, disturbed sleep etc. reported by participant. * Individuals willing to consume an investigational product from bovine source. * Individuals willing to complete all study-related and clinical study visits as per protocol. Exclusion Criteria: * Clinically diagnosed with Attention Deficit Hyperactivity Disorder (ADHD). * Clinically diagnosed with mental disorders (diagnostic and statistical manual of mental disorders: DSM-5-TR), namely but not limited to epilepsy, anxiety, depression or Alzheimer's disease. * Individuals with a medical history of cardiac disease, respiratory disorders, kidney disorder, liver disorder, or seizure disorders or other chronic health conditions requiring medication. * Individuals with uncontrolled hypertension (systolic blood pressure greater than or equal to 140 mmHg or diastolic blood pressure greater than or equal to 90 mmHg). * Individuals with uncontrolled diabetes (fasting blood glucose (FBG) greater than equal to 126 mg/dl). * Individuals with history of hypersensitivity to any components of the investigational product. * Those taking prescription medication or dietary supplements that affect cognitive function within 30 days prior to screening. * Head injury immediately preceding cognitive deterioration. * Consumption of excessive amounts of caffeine (more than 4-5 cups per day) and caffeine-containing foods or beverages. * Current smokers. * Those who are deemed unable to comply with the test requirements or otherwise deemed unsuitable according to the Investigator's opinion. * Females who are pregnant/planning to be pregnant/lactating or taking any oral contraceptives. * History of drug or alcohol addiction or abuse with the past 12 months.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Bhaktisiddhant Hospital
Pimpri-Chinchwad, Maharashtra, 411044, India
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Gurukrupa Hospital
Thane, Maharashtra, 400601, India
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New Manak Healthcare Care Hospital
Navi Mumbai, Maharashtra, 400706, India
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Omkar ENT Hospital and Research Centre
Nashik, Maharashtra, 422002, India
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Pawana Hospital
Pune, Maharashtra, 410506, India
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Punawale Multispecialty Hospital
Pimpri-Chinchwad, Maharashtra, 411033, India
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Samarth Hospital
Nashik, Maharashtra, 423203, India
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Silver Birch Multispecialty Hospital
Pune, Maharashtra, 411041, India
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