New drug AON-D21 tested in ICU pneumonia patients – could it speed recovery?
NCT ID NCT05962606
First seen Jan 05, 2026 · Last updated May 23, 2026 · Updated 21 times
Summary
This study tested an experimental drug called AON-D21 in 150 adults with severe pneumonia who needed breathing support in the ICU. Half received the drug and half received a placebo, both alongside standard care. The main goals were to check if the drug is safe and if it helps patients stop needing breathing support sooner.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Assistance Publique-Hopitaux de Paris (AP-HP)
Paris, France
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CHRU de Tours Hôpital Bretonneau
Tours, France
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CHU Dupuytren
Limoges, France
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Centre Hospitalier Argenteuil
Argenteuil, France
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Centre Hospitalier Départemental Vendée
La Roche-sur-Yon, France
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Centre Hospitalier de Melun
Melun, France
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Charité - Universitätsmedizin Berlin
Berlin, Germany
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Clinique Saint Pierre
Ottignies, Belgium
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Cliniques Universitaires Saint-Luc
Brussels, Belgium
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Cologne-Merheim Hospital Lung Clinic
Cologne, Germany
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Hospital Clinico San Carlos
Madrid, Spain
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Hospital Doctor Josep Trueta
Girona, Spain
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Hospital Universitari Vall d'Hebron
Barcelona, Spain
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Hospital Universitari i Politecnic La Fe de Valencia
Valencia, Spain
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Hotel Dieu - CHU Nantes
Nantes, France
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Hôpital Nord Franche Comté
Trévenans, France
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Liverpool University Hospitals NHS Foundation Trust
Liverpool, United Kingdom
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Mid Yokshire Teaching NHS Trust
Wakefield, United Kingdom
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Nouvel Hôpital Civil
Strasbourg, France
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Royal Berkshire Foundation Trust
Reading, United Kingdom
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Universitaetsklinikum Giessen und Marburg GmbH
Giessen, Germany
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University College London
London, United Kingdom
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University Hospital Bristol and Weston NHS
Bristol, United Kingdom
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University Hospital of Wales
Cardiff, United Kingdom
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University Hospitals Plymouth NHS Trust, Derriford Hospital
Plymouth, United Kingdom
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University of Alabama at Birmingham Heersink School of Medicine
Birmingham, Alabama, 35233, United States
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York Hospital
York, United Kingdom
Conditions
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