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Shorter antibiotic course may be just as effective for kids with pneumonia

NCT ID NCT07647835

Disease control Sponsor: Khyber Teaching Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a 3-day course of amoxicillin works as well as a 5-day course for children aged 3 months to 5 years with uncomplicated pneumonia. The goal is to see if shorter treatment can reduce side effects, lower costs, and fight antibiotic resistance. About 250 children will take part, and their recovery will be checked at day 14.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Early phase 1

The earliest testing in people: a first look at safety, in a very small group.

Participants

About 250 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jun 2026

An estimate. Start dates often move.

Expected to finish

Jun 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

3 months to 5 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion criteria: * Age; ≥ 3 months to 5 years * Fever; recorded temperature of ≥100.4 f or guardian reported fever within 2 days * Cough; observed or reported within 3 days * Tachypnea; * 3 months to 1 years ≥ 50 breaths per minute * 1 years to 5 years ≥ 40 breaths per minute * C- reactive protein ≥ 40 * White blood cells ≥ 12200 * Chest X-ray; * Presence of a dense opacity occupying a portion or whole of lobe with or without air Broncho grams. Exclusion criteria: * Patient who is Lethargic and unable to tolerate orally. * Capillary refill greater than 2 second * Chronic lung disease * Congenital heart disease or sickle cell anemia patient * Immunocompromised patient * malnourished * Known or suspected tuberculosis patient * Patient has used prior antibiotic within 2 days * Allergic to penicillin or amoxicillin * C-reactive protein greater than 72 * White blood cells greater than 25000 * Chest x rays show linear or patchy or peri bronchial opacity * Presence of pleural effusions * Empyema, lung abscess, necrotizing pneumonia or pneumatocele * Other alternative diagnosis like wheezing syndrome (Bilateral wheezing on auscultation)

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Conditions

The condition(s) this trial relates to.

Community-Acquired Pneumonia pneumonia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Childhood pneumonia Community-acquired pneumonia

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Khyber Teaching Hospital

    Peshawar, Khyber Pakhtunkhwa, 25000, Pakistan

More trials for these conditions

Other studies related to the condition(s) this trial covers.