COMMUNITY-ACQUIRED PNEUMONIA

This study is testing whether treating a common herpes virus improves survival in critically ill pneumonia patients on breathing machines. Researchers will randomly assign over 600 patients to receive either the antiviral drug acyclovir or no antiviral treatment for 10 days. The …

This study is testing whether adding an immune-boosting drug called trimodulin to standard hospital care helps adults with severe pneumonia who are on a breathing machine. About 590 hospitalized patients will receive either the drug or a placebo for 5 days, in addition to their r…

This study is testing if giving hospitalized pneumonia patients a stronger dose of a common blood thinner (heparin) can prevent dangerous blood clots and help them recover better. It will involve 4,000 adults who are in the hospital for pneumonia but are not yet in intensive care…

This study is testing if a 'watch and wait' strategy for antibiotics is as safe and effective as giving them right away for children with mild pneumonia. About 2,000 children, aged 1 to 6 years, will be randomly assigned to either get antibiotics immediately or only if they don't…

This study aims to find out if a simpler, narrower-spectrum antibiotic (amoxicillin) works as well as a stronger, broader-spectrum one (amoxicillin/clavulanate) for treating community-acquired pneumonia in people aged 65 and older who are hospitalized outside the intensive care u…

This study compares two common antibiotics—azithromycin and doxycycline—for adults hospitalized with pneumonia. Researchers want to see which one helps patients spend fewer days in the hospital and recover faster. The trial includes 1,120 participants who are already receiving st…

This study is testing if giving an antibiotic called clarithromycin early to adults with pneumonia can prevent the infection from worsening into life-threatening sepsis. Doctors will use a specific blood test result to identify which pneumonia patients are at the highest risk for…

This study aims to learn more about how common respiratory infections like colds, flu, and pneumonia progress over time. Researchers will observe 1000 adults who visit a fever clinic, collecting information on their symptoms and test results. The goal is to understand the natural…

This study aims to see if measuring frailty (overall physical weakness and vulnerability) in older adults arriving at the emergency room with pneumonia can better predict who might die in the hospital or within 30 days. Researchers will observe 150 patients aged 65 and older to c…