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Could a common cold sore virus be linked to Alzheimer's? new study tests antiviral treatment

NCT ID NCT04710030

First seen Dec 17, 2025 · Last updated May 01, 2026 · Updated 18 times

Summary

This study tested whether a common antiviral drug, valacyclovir, could slow memory decline in people with mild cognitive impairment (MCI) who also carry the herpes simplex virus. Fifty participants took either the drug or a placebo for 52 weeks. The goal was to see if treating the virus could reduce brain changes linked to Alzheimer's disease. This was an early-phase trial to gather initial evidence.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • New York State Psychiatric Institute

    New York, New York, 10032, United States

Conditions

Explore the condition pages connected to this study.