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Antioxidant pill may shield skin from city smog

NCT ID NCT07793123

Symptom relief Sponsor: Robertet SA Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 28, 2026 · Last updated Sep 17, 2026 · Updated 2 times

Summary

Researchers are testing whether a daily oral antioxidant supplement can improve skin radiance in healthy women aged 35 to 65 who live in urban areas and are exposed to air pollution. The trial gives participants either the supplement or a placebo for 90 days, then measures skin radiance, tone, pigmentation, and other skin health markers. The goal is to see if the supplement can counteract some of the skin dullness linked to city living.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
an oral antioxidant dietary supplement
What this could lead to
If it works, this could point toward a simple daily supplement that helps protect skin from the visible effects of urban air pollution.
What could go wrong
This is a small, early-stage trial with 60 participants, so results may not apply to everyone. The supplement may not improve skin radiance, and any benefits could be modest.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2026

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

35 to 65 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Healthy female subjects aged 35 to 65 years. * Fitzpatrick skin phototype II to IV. * Any skin type. * Dull and uneven skin complexion. * Living in an urban environment and exposed to pollution. * No change in hormonal treatment within the past 3 months. * Able to understand the study procedures and provide informed consent. * Willing and able to comply with study requirements. * Written informed consent obtained. * Covered by health insurance. * Willing to avoid unprotected sun exposure and use SPF 50 sunscreen throughout the study. Exclusion Criteria: * Pregnant or breastfeeding women, or women planning to become pregnant during the study. * Current use of dietary supplements or vitamin supplements. * Participation in another clinical trial involving a cosmetic product, drug, or medical device. * Use of oral or injectable corticosteroids within the past 3 months. * Current treatment with immunosuppressive agents, chemotherapy, or radiotherapy. * History of autoimmune disease or connective tissue disorder. * Presence of an active dermatological condition that could affect study assessments. * Following a vegetarian, vegan, or weight-loss diet. * Not covered by health insurance. * Participation in another clinical study during the exclusion period. * Individuals considered vulnerable according to applicable regulations.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Healthy women

Contacts and locations

Locations

  • Gredeco

    Paris, 75 013, France

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