Antioxidant pill may shield skin from city smog
NCT ID NCT07793123
First seen Aug 28, 2026 · Last updated Aug 28, 2026
Summary
Researchers are testing whether a daily oral antioxidant supplement can improve skin radiance in healthy women aged 35 to 65 who live in urban areas and are exposed to air pollution. The trial gives participants either the supplement or a placebo for 90 days, then measures skin radiance, tone, pigmentation, and other skin health markers. The goal is to see if the supplement can counteract some of the skin dullness linked to city living.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- an oral antioxidant dietary supplement
- What this could lead to
- If it works, this could point toward a simple daily supplement that helps protect skin from the visible effects of urban air pollution.
- What could go wrong
- This is a small, early-stage trial with 60 participants, so results may not apply to everyone. The supplement may not improve skin radiance, and any benefits could be modest.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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35 to 65 years
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Healthy female aged 35 to 65 years * Fitzpatrick skin phototype II to IV * All skin types * Dull and uneven skin tone * Living in an urban environment and exposed to air pollution * Able to comply with study procedures * Written informed consent provided Exclusion Criteria: * Pregnant or breastfeeding * Current use of dietary supplements or vitamin supplements * Specific dietary restrictions * Unstable medication affecting water retention * Active medical disease * Facial dermatological disorder * Participation in another clinical trial * Vulnerable populations according to French regulations
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Gredeco
Paris, 75 013, France
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