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Mushroom extract shows promise against fatigue in small trial

NCT ID NCT06902662

Symptom relief Sponsor: National Taiwan Sport University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a mushroom extract called Sanghuangporus sanghuang (SS-MN4) can reduce fatigue and improve muscle performance in healthy young men. 58 participants took either the extract or a placebo daily for 42 days. Researchers measured muscle damage, strength, and stress hormones to see if the supplement helps.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Sanghuangporus sanghuang mushroom extract (SS-MN4)
What this could lead to
If it works, this could support a natural supplement to help reduce exercise fatigue and improve muscle function in healthy adults.
What could go wrong
This is a small, early-stage trial in healthy young men only, so results may not apply to older or less healthy people. The supplement may show no benefit over placebo.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

58 people

The number who actually took part.

Started

Apr 2025

Finished

Oct 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 35 years

Sex

Male participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Healthy male participants aged between 20 and 35 years * Non-smokers and non-drinkers * Not currently taking any dietary supplements or medications * Normal liver and kidney function * No chronic diseases such as cardiovascular disease * Willing and able to provide written informed consent * Able to comply with study procedures and schedule Exclusion Criteria: * Current or past diagnosis of any cardiovascular, liver, kidney, or metabolic disease * Regular use of dietary supplements, sports nutrition products, or energy drinks * Known food allergies or intolerances, particularly to mushrooms or herbal products * Engaging in regular resistance or endurance training in the last 6 months * Currently taking medications that may interfere with study outcomes * Smoking or alcohol consumption * Participation in other clinical trials within the last 3 months

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Nutritional supplementation Physical performance

Contacts and locations

Locations

  • National Taiwan Sport University, Graduate Institute of Sports Science

    Taoyuan, 333325, Taiwan

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