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Mind over muscle: could a sugar pill boost your workout like caffeine?

NCT ID NCT07748429

Knowledge-focused Sponsor: Poznan University of Physical Education Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 05, 2026 · Last updated Sep 18, 2026 · Updated 2 times

Summary

This study asks whether simply believing you've taken caffeine can improve physical and mental performance, even when you've actually received a placebo. Healthy adults aged 20–30 will complete four cycling sessions, sometimes getting real caffeine and sometimes a dummy pill, while researchers track heart rate, stress hormones, and work output. The goal is to understand how expectations shape our psychophysiological limits and to refine a mathematical model of the placebo effect.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Caffeine (6 mg/kg) and placebo (starch capsule)
What this could lead to
If expectations alone can measurably boost physical and cognitive performance, this could point toward non-drug ways to enhance athletic and mental output.
What could go wrong
This is a small mechanistic study in healthy young adults, so results may not apply to athletes or patients. The placebo effect is notoriously variable and hard to reproduce.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 80 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jan 2027

An estimate. Start dates often move.

Expected to finish

Mar 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 35 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age between 20 and 35 years, * Healthy adults, * Regular physical activity, but not professional athletes, * Normal or corrected-to-normal vision, * Habitual caffeine consumption. Exclusion Criteria: * History of neurological, psychiatric, cardiovascular, or metabolic disorders, * Current use of medication or supplements affecting the central nervous system, * Musculoskeletal injuries that would impair physical performance, * No habitual caffeine consumption or severe negative side effects of caffeine, * Diagnosed sleep disorders or chronic fatigue, * Diagnosed major depressive disorder or other severe psychiatric conditions, * Presence of any menstrual disorders, * Inability to attend all experimental study visits.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cognitive performance Physical performance Placebo effect

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Poznan University of Physical Education

    Poznan, Wielkopolska, Poland

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