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Mind over muscle: could a fake pill enhance Real-World athletic performance?

NCT ID NCT07742150

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 03, 2026 · Last updated Aug 04, 2026 · Updated 1 time

Summary

This study explores whether believing you've taken caffeine can improve physical performance in real-world sports settings. Healthy, physically active adults will be randomly assigned to receive caffeine, a placebo (starch capsule), or no treatment, then perform sport-specific exercise tests. Researchers will measure performance and heart rate to separate the drug's actual effects from those driven by expectation. The goal is to understand how the placebo effect works outside the lab and whether it can be harnessed to boost athletic and cognitive performance.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Caffeine (6mg/kg) and placebo (starch capsule) and sham (no treatment)
What this could lead to
If the placebo effect is strong, it could lead to non-drug strategies to enhance athletic performance and cognitive function in real-world settings.
What could go wrong
The trial is early-stage and results may not apply broadly. The placebo effect may be small or inconsistent across different sports and individuals.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 120 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Mar 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 35 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age between 20 and 35 years, * Healthy adults, * Regular physical activity, * Normal or corrected-to-normal vision, * Habitual caffeine consumption. Exclusion Criteria: * History of neurological, psychiatric, cardiovascular, or metabolic disorders, * Current use of medication or supplements affecting the central nervous system, * Musculoskeletal injuries that would impair physical performance, * No habitual caffeine consumption or severe negative side effects of caffeine, * Diagnosed sleep disorders or chronic fatigue, * Diagnosed major depressive disorder or other severe psychiatric conditions, * Presence of any menstrual disorders, * Inability to attend all experimental study visits.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • Poznan University of Physical Education

    Poznan, Greater Poland Voivodeship, Poland

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