Teen brain study seeks clues to Anorexia's grip
NCT ID NCT05357053
First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study looks at how anorexia nervosa changes brain function and metabolism in teenage girls. Researchers will use brain scans to compare 33 adolescents with and without the condition, then follow them for three years. The goal is to better understand the disease and find new ways to predict or influence its course.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this research could point toward new ways to predict how anorexia nervosa progresses and identify targets for future treatments.
- What could go wrong
- This is an observational study with only 33 participants, so findings may not apply to all patients. It is designed to gather knowledge, not to test a treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
33 people
The number who actually took part.
- Started
-
Jan 2022
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population comprises 50 female adolescents with anorexia nervosa meeting the inclusion criteria. They are compared with 50 age and sex-matched healthy normal weight controls.
- Ages
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13 to 17 years
- Sex
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Female participants only
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion criteria for anorexia nervosa patients: * Female sex * Age 13-17 years * Body mass index \< 17.5 kg/m2 * Currently fulfilling modified Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) diagnosis criteria for anorexia nervosa with or without amenorrhea * Anorexia nervosa diagnosed within 2 yers Inclusion criteria for healthy controls: * Female sex * Age 13-17 years * Body mass index 18,5-25 kg/m2 * No lifetime history of obesity (Body mass index ≥ 30) or eating disorders Exclusion criteria: * Any chronic illness or medication that could affect glucose metabolism or neurotransmission * Any other current mental disorder (excluding anorexia nervosa for the patient participants) * Severe previous mental disorder (excluding anorexia nervosa for the patient participants) * Smoking of tobacco, snuffing, or use of narcotics * Abusive use of alcohol
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Turku PET Centre
Turku, 20521, Finland
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a parent support group help teens with both autism and anorexia?
- Lab-Grown brain cells could unlock Anorexia's secrets
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