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Which anesthetic best reveals seizure spots in the brain?

NCT ID NCT07165262

Knowledge-focused Sponsor: Children's Cancer Hospital Egypt 57357 Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study compares two anesthetic drugs, fentanyl and ketamine, to see which one better helps surgeons find seizure-causing brain tissue during epilepsy surgery in children. Eighty-eight children aged 2-18 with brain tumors and epilepsy will receive one of the drugs during surgery. The goal is to improve the accuracy of brain mapping, not to cure the disease.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
fentanyl and ketamine
What this could lead to
If successful, this could help surgeons better locate seizure-causing brain tissue during surgery, potentially improving outcomes for children with epilepsy.
What could go wrong
This is a small, early-phase study focused on measuring brain activity, not on curing disease. The results may not apply to all patients or lead to direct treatment benefits.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

88 people

The number who actually took part.

Started

Aug 2025

Expected to finish

Mar 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

2 to 18 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age (2-18) Years scheduled for brain tumor excision with aid of ECOG * ASA physical status (II-III). * Patient undergoing brain surgery with epileptic focus. Exclusion Criteria: * guardian refusal. * Patients with hypertension, ischemic heart disease, arrhythmia, or respiratory or renal dysfunction.

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Conditions

The condition(s) this trial relates to.

brain cancer brain neoplasm epilepsy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Brain tumor Epilepsy

Contacts and locations

Locations

  • Children Cancer Hospital 57357

    Cairo, 11617, Egypt

  • Children's Cancer Hospital Egypt 57357

    Cairo, 11511, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.