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New study tests bone grafting to make dental implants more reliable

NCT ID NCT07427784

Disease control Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether placing a bone graft in the tooth socket right after extraction helps preserve the jawbone for future dental implants. Fifty adults who need implants will receive the graft and be followed with scans and checkups. The goal is to see if this approach allows standard-sized implants to be placed without extra bone surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
bone graft
What this could lead to
If successful, this could show that bone grafting after tooth extraction helps standard dental implants work better and last longer.
What could go wrong
This is a small, early-stage study with only 50 participants. It may not prove the procedure works for everyone, and bone grafting has risks like infection or graft failure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 50 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Mar 2026

An estimate. Start dates often move.

Expected to finish

Mar 2031

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients aged 18 years and older requiring bone regeneration with an alveolar ridge preservation technique prior to implant rehabilitation will be included in the study.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients requiring alveolar ridge preservation procedures prior to implant rehabilitation of edentulous sites; * Age \> 18; * Achievement of FMPS and FMBS ≤ 15%; * Signed written informed consent to participate in the study. Exclusion Criteria: * Uncontrolled diabetes or hypertension; * Uncontrolled periodontal disease; * Inability to perform consistent and continuous follow-up; * Pregnancy or breastfeeding; * Inability to provide written informed consent.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Alveolar ridge preservation

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Catholic University of the Sacred Heart

    Roma, 00168, Italy

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