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Scientists hunt for hidden signs of ALS and FTD in skin and tears

NCT ID NCT06856850

First seen Apr 07, 2026 · Last updated Jun 22, 2026 · Updated 11 times

Summary

This study aims to find biological markers (biosignatures) in people with ALS and FTD to make diagnosis more precise. Researchers will analyze samples like spinal fluid, skin, and tears from 230 participants using advanced techniques. The goal is to create a 'disease fingerprint' that helps doctors diagnose earlier and track how the disease progresses.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Azienda Ospedaliero Universitaria di Sassari

    NOT_YET_RECRUITING

    Sassari, 07100, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Consorzio Interuniversitario Risonanze Magnetiche Metallo Proteine (CIRMMP)

    NOT_YET_RECRUITING

    Sesto Fiorentino, 50019, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Fondazione IRCCS Istituto Neurologico Carlo Besta

    RECRUITING

    Milan, 20133, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Università degli Studi di Napoli "Federico II"

    NOT_YET_RECRUITING

    Naples, 80131, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could lead to better, earlier diagnosis of ALS and FTD and help track disease progression more accurately.

What could go wrong

This is an early-stage observational study, not a treatment trial. The biomarkers identified may not prove useful in real-world clinical settings.

Conditions

The condition(s) this trial relates to.

amyotrophic lateral sclerosis frontotemporal dementia pseudotumor cerebri psychiatric disorder semantic dementia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.