New genetic drug targets fatty liver disease in early human trial
NCT ID NCT05648214
First seen Jan 11, 2026 · Last updated Apr 30, 2026 · Updated 19 times
Summary
This early-stage study tests an experimental drug called ALN-PNP in healthy adults and people with a type of fatty liver disease (MASLD) who have a specific gene variant. The main goal is to check safety and how the body processes the drug. Researchers will also measure changes in liver fat and look for side effects over time.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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California Clinical Trials Medical Group
COMPLETEDGlendale, California, 91206, United States
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Genoma Research Group, Inc
RECRUITINGMiami, Florida, 33173, United States
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Med Research of Florida, LLC
RECRUITINGMiami, Florida, 33186, United States
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Pioneer Research Solutions
RECRUITINGHouston, Texas, 77099, United States
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Tandem Clinical Research
RECRUITINGMarrero, Louisiana, 70072, United States
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Velocity Clinical research
RECRUITINGLos Angeles, California, 90057, United States
Conditions
Explore the condition pages connected to this study.