New drug targets fatty liver in early human trial
NCT ID NCT05648214
First seen Jan 11, 2026 · Last updated Jun 12, 2026 · Updated 24 times
Summary
This study tests an experimental drug called ALN-PNP for people with a type of fatty liver disease (MASLD) who have a specific gene variant. It is a first-in-human trial, meaning it is the first time this drug is given to people. The main goals are to check if the drug is safe, tolerable, and how it works in the body. The study includes healthy volunteers and people with MASLD, and will measure changes in liver fat.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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California Clinical Trials Medical Group
COMPLETEDGlendale, California, 91206, United States
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Genoma Research Group, Inc
RECRUITINGMiami, Florida, 33173, United States
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Med Research of Florida, LLC
RECRUITINGMiami, Florida, 33186, United States
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Pioneer Research Solutions
RECRUITINGHouston, Texas, 77099, United States
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Tandem Clinical Research
RECRUITINGMarrero, Louisiana, 70072, United States
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Velocity Clinical research
RECRUITINGLos Angeles, California, 90057, United States
Conditions
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