Sugar substitute allulose tested for Calorie-Burning boost
NCT ID NCT06515340
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed study looked at how allulose, a low-calorie sweetener, affects how many calories the body burns, which fuels it uses, blood sugar, and hunger. Eleven healthy adults with normal weight took different doses (5, 10, or 20 grams) and were monitored for several hours. The goal was to see if allulose could increase calorie burning or help control appetite, which might be useful for weight management.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- allulose
- What this could lead to
- If results show allulose boosts calorie burning or controls appetite, it could point toward a natural sweetener that helps with weight management.
- What could go wrong
- This was a very small study (11 people) in healthy adults only. Findings may not apply to the general population, and any effects seen might be too small to matter in real life.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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11 people
The number who actually took part.
- Started
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Jul 2024
- Finished
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Mar 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 45 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Participants (18 - 45 years) who are considered healthy, are non-smokers, and have a body mass index (BMI) between 20 and 24.9 kg/m2 \[World Health Organization classification of normal weight BMI\]. Exclusion Criteria: * Participants who have a fasting plasma glucose \> 5.5 mmol/L indicative of impaired fasting glucose, previously diagnosed diabetes, known or uncertain pregnancy status at the screening visit, gastrointestinal disease, liver or kidney disease, have undergone a major medical or surgical event within the past 6 months, were or are on a diet, skip breakfast, smoke or have taken medication which would be a potential confounder with effects on metabolic and intake regulation. * Those unable to complete the testing protocols or are intolerant or allergic to test-day ingredients.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Centre for Urban Innovation (CUI-109)
Toronto, Ontario, M5B 2K3, Canada
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