Sugar swap showdown: allulose vs. stevia vs. sucralose – which wins for metabolism?
NCT ID NCT07231133
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at how three different sweeteners—allulose, sucralose, and stevia—affect metabolism, blood sugar, and hunger when eaten with a meal. Researchers measured energy use and appetite in 12 healthy adults of normal weight. The goal was to understand how these sweeteners compare in their short-term effects on the body.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
12 people
The number who actually took part.
- Started
-
May 2025
- Finished
-
Aug 2025
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 45 years
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: \- Participants (18 - 45 years) who are considered healthy, are non-smokers, and have a body mass index (BMI) between 20 and 24.9 kg/m2 \[World Health Organization classification of normal weight BMI\]. Exclusion Criteria: * Participants who have a fasting plasma glucose \> 5.5 mmol/L indicative of impaired fasting glucose, previously diagnosed diabetes, known or uncertain pregnancy status at the screening visit, gastrointestinal disease, liver or kidney disease, have undergone a major medical or surgical event within the past 6 months, were or are on a diet, skip breakfast, smoke or have taken medication which would be a potential confounder with effects on metabolic and intake regulation. * Those unable to complete the testing protocols or are intolerant or allergic to test-day ingredients.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Diet-induced thermogenesis are added.
Genom att skicka in godkänner du våra Användarvillkor
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Toronto Metropolitan University
Toronto, Ontario, Canada
More trials for these conditions
Other studies related to the condition(s) this trial covers.