Immune cell combo offers new hope for patients with stubborn autoimmune conditions

NCT ID NCT06991114

Recruiting now Disease control Sponsor: Artiva Biotherapeutics, Inc. Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 24, 2026 · Updated 32 times

Summary

This study is testing a new treatment for people with certain autoimmune diseases (rheumatoid arthritis, Sjögren's disease, myositis, or scleroderma) that have not responded to standard therapies. The treatment combines a natural killer cell therapy called AlloNK with the drug rituximab. The goal is to see if this combination is safe and can help control disease activity. About 90 adults will take part in this early-phase trial.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Artiva Investigational Site Arlington
RECRUITING

Arlington, Texas, 76012, United States
Artiva Investigational Site Belgrade
RECRUITING

Belgrade, Belgrade, Serbia
Artiva Investigational Site Bellaire
RECRUITING

Bellaire, Texas, 77401, United States
Artiva Investigational Site Bonn
RECRUITING

Bonn, Bonn, Germany
Artiva Investigational Site Brasília
RECRUITING

Brasília, Brasília, Brazil
Artiva Investigational Site Brescia
RECRUITING

Brescia, 25125, Italy
Artiva Investigational Site Bucharest
RECRUITING

Bucharest, 50474, Romania
Artiva Investigational Site Bucuresti
RECRUITING

Bucharest, 20125, Romania
Artiva Investigational Site Bydgoszcz
RECRUITING

Bydgoszcz, Bydgoszcz, Poland
Artiva Investigational Site Charleston
RECRUITING

Charleston, South Carolina, 29407, United States
Artiva Investigational Site Charlotte
RECRUITING

Charlotte, North Carolina, 28207, United States
Artiva Investigational Site Charlotte
RECRUITING

Charlotte, North Carolina, 28625, United States
Artiva Investigational Site Chula Vista
RECRUITING

Chula Vista, California, 92108, United States
Artiva Investigational Site Covina
RECRUITING

Covina, California, 91723, United States
Artiva Investigational Site Cuiabá
RECRUITING

Cuiabá, Cuiabá, Brazil
Artiva Investigational Site Gainesville
RECRUITING

Gainesville, Georgia, 30501, United States
Artiva Investigational Site Hixson
RECRUITING

Hixson, Tennessee, 37343, United States
Artiva Investigational Site Iowa
RECRUITING

Iowa City, Iowa, 52242, United States
Artiva Investigational Site Iowa Great Falls
RECRUITING

Great Falls, Montana, 59405, United States
Artiva Investigational Site Irving
RECRUITING

Irving, Texas, 75061, United States
Artiva Investigational Site Jackson
RECRUITING

Jackson, Tennessee, 38305, United States
Artiva Investigational Site Jupiter
RECRUITING

Jupiter, Florida, 33458, United States
Artiva Investigational Site Katy
RECRUITING

Katy, Texas, 77494, United States
Artiva Investigational Site Los Alamitos
RECRUITING

Los Alamitos, California, 90720, United States
Artiva Investigational Site Los Angeles
RECRUITING

Los Angeles, California, 90027, United States
Artiva Investigational Site Marseille
RECRUITING

Marseille, 13005, France
Artiva Investigational Site Mesquite
RECRUITING

Mesquite, Texas, 75150, United States
Artiva Investigational Site Miami
RECRUITING

Miami, Florida, 33143, United States
Artiva Investigational Site Montpellier
RECRUITING

Montpellier, 34090, France
Artiva Investigational Site Munchen
RECRUITING

München, 80336, Germany
Artiva Investigational Site Norcross
RECRUITING

Norcross, Georgia, 30092, United States
Artiva Investigational Site Phoenix
RECRUITING

Phoenix, Arizona, 85037, United States
Artiva Investigational Site Plantation
RECRUITING

Plantation, Florida, 33324, United States
Artiva Investigational Site Plovdiv
RECRUITING

Plovdiv, Plovdiv, Bulgaria
Artiva Investigational Site Porto Alegre
RECRUITING

Porto Alegre, Porto Alegre, Brazil
Artiva Investigational Site Red Oak
RECRUITING

Red Oak, Texas, 75154, United States
Artiva Investigational Site Rio Grande
RECRUITING

Rio Grande, Porto Alegre, Brazil
Artiva Investigational Site Roanoke
RECRUITING

Roanoke, Virginia, 24016, United States
Artiva Investigational Site Santa Ana
RECRUITING

Santa Ana, California, 92706, United States
Artiva Investigational Site Sao Paulo
RECRUITING

São Paulo, São Paulo, Brazil
Artiva Investigational Site Sevila
RECRUITING

Seville, 41701, Spain
Artiva Investigational Site Sofia
RECRUITING

Sofia, 1612, Bulgaria
Artiva Investigational Site Statesville
RECRUITING

Statesville, North Carolina, 27103, United States
Artiva Investigational Site São Paulo
RECRUITING

São Paulo, São Paulo, Brazil
Artiva Investigational Site Toulouse
RECRUITING

Toulouse, 31059, France
Artiva Investigational Site Tucson
RECRUITING

Tucson, Arizona, 85748, United States
Artiva Investigational Site Tuscaloosa
RECRUITING

Tuscaloosa, Alabama, 35406, United States
Artiva Investigational Site Tustin
RECRUITING

Tustin, California, 92780, United States
Artiva Investigational Site Vila Nova De Gaia
RECRUITING

Vila Nova de Gaia, 4434, Portugal
Artiva Investigational Site Warszawa
RECRUITING

Warsaw, Warszawa, Poland
Artiva Investigational Site Willowbrook
RECRUITING

Willowbrook, Illinois, 60527, United States
Artiva Investigational Site Woodland
RECRUITING

Woodland, Texas, 77382, United States

Conditions

Explore the condition pages connected to this study.

IDIOPATHIC INFLAMMATORY MYOPATHIES (IIMS) IIM MYOSITIS REFRACTORY RHEUMATOID ARTHRITIS (RA) RHEUMATOID ARTHRITIS (RA) SCLERODERMA SJOGREN SYNDROME SJOGREN SYNDROME SJOGRENS DISEASE SJOGRENS DISEASE SYSTEMIC SCLEROSIS (SSC) SYSTEMIC SCLEROSIS (SSC)