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Can virtual reality help fight alcohol addiction?

NCT ID NCT06333457

Knowledge-focused Sponsor: Charite University, Berlin, Germany Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether a strong sense of 'presence' during virtual reality therapy could help people with alcohol dependence manage cravings and avoid relapse. Sixty abstinent patients who had recently completed withdrawal treatment took part. Researchers measured craving levels and tracked relapse rates over time.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Virtual reality cue-exposure therapy (VR-CET)
What this could lead to
If successful, this could help refine VR-based treatments for alcohol dependence by showing how a strong sense of presence might reduce craving and relapse.
What could go wrong
This is a small, completed observational study, not a large treatment trial. Results may not apply to all patients, and VR therapy is not yet a standard treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

60 people

The number who actually took part.

Started

Apr 2024

Finished

Mar 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients with alcohol dependence treated in the inpatient or outpatient psychiatric clinics or day clinics of the Psychiatric University Hospital Charité at St. Hedwig-Hospital/ Department of Psychiatry and Neurosciences Campus Charité Mitte/ Theodor-Wenzel Werk Berlin / Jüdisches Krankenhaus Berlin / Vivantes Auguste-Viktoria-Klinikum

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * age: 18-65 years * diagnosis of alcohol dependence according to ICD-10 (F10.2) * completed in-patient withdrawal treatment during the last 3 months * history of alcohol craving, confrmed via craving questionnaires * able to provide written informed consent Exclusion Criteria: * substance dependence other than alcohol and nicotine * current alcohol intoxication (randomly tested via measurement of breath alcohol concentration) * unable to understand the study information, consent form or principles of the study * abstinence for less than 7 days or on-going consumption of alcohol * severe neuropsychiatric disorder, e.g., schizophrenia spectrum disorders, bipolar afective disorder or substantial cognitive impairment * somatic diseases for which VR is associated with risks, e.g. photosensitive epilepsy * acute suicidality or acute endangerment of others * concurrent pharmacological treatment targeting AUD (i.e. benzodiazepines) or craving (i.e. acamprosate, disulfram, naltrexone, nalmefene)

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Conditions

The condition(s) this trial relates to.

alcohol abuse alcohol dependence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Alcohol dependence

Contacts and locations

Locations

  • Psychiatric University Hospital Charité at St. Hedwig Hospital

    Berlin, State of Berlin, 10115, Germany

More trials for these conditions

Other studies related to the condition(s) this trial covers.