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Walking your way to a better brain after injury?

NCT ID NCT04243226

Symptom relief Sponsor: National Defense Medical Center, Taiwan Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a guided, telehealth-based aerobic walking program could improve thinking, mood, and quality of life in people who had a traumatic brain injury (TBI). Researchers enrolled 112 participants and measured changes in brain blood flow, walking ability, and mental health. The goal was to develop a safe exercise plan that TBI patients could follow at home.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
telehealth-based aerobic walking exercise
What this could lead to
If it works, this could point toward a safe, accessible exercise program to help TBI patients think more clearly, feel less depressed, and enjoy a better quality of life.
What could go wrong
This is a completed early-stage study with 112 participants, so results may not apply to all TBI patients. Exercise benefits can vary, and the study relied on self-reported and device-based measures.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

112 people

The number who actually took part.

Started

Jan 2020

Finished

Jun 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Patients who have been diagnosed with mild traumatic brain injury at the emergency department 2. GCS score of 14-15 at the emergency department or patients with moderate brain injury (GCS score of 8-13 3. Brain injury Patients more than three months after discharge 4. Can communicate in Chinese and Taiwanese 5. Patients who have good audio-visual ability to complete tests and data filling 6. Patients are willing to sign a consent form to participate in the research. 7. Each subject was able to walk on their own, communicate freely and live in Taipei or Greater Taipei. Exclusion Criteria: 1. Exclude those with severe impairment of cognition, emotions and executive function caused by prefrontal lobe injury 2. Exclude patients with brain injury due to head puncture. 3. Regularly perform moderate-intensity aerobic exercise.

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Conditions

The condition(s) this trial relates to.

psychiatric disorder traumatic brain injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cardiology Psychiatry

Contacts and locations

Locations

  • TSGH

    Taipei, Taiwan

More trials for these conditions

Other studies related to the condition(s) this trial covers.