New study aims to decode pain in kidney disease patients

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Patients with ADPKD * Subject is ≥ 12 years old. * Subject is diagnosed with ADPKD. Healthy volunteers * Subject is ≥ 12 years old. * Subject is in good general health, based on medical history and vital signs. * Subject is matched to the patient group for age, sex and BMI. Exclusion Criteria: Patients with ADPKD * Subject has eczema, scleroderma, psoriasis, dermatitis, or any other abnormality on the skin of the dominant hand and/or lower back which, in the investigator's opinion, might interfere with the study assessments. * Subject is currently undergoing dialysis, had a kidney transplant or is a user of tolvaptan. * Female who is pregnant or breastfeeding. * Simultaneous participation in another study which, in the investigator's opinion, might confound the results of the study. * Subject is unable to refrain from drinking alcohol 24 hours prior to each study visit, and/or consumes ≥ 3 alcoholic consumptions per day. * Subject is a regular user of cannabis, any illicit drugs and/or has a history of drug abuse. * Subject is unable to refrain from drinking caffeinated beverages (such as coffee, tea, cola,…) 24 hours prior to each study visit. * Subject has used concomitant drugs and/or treatments in a period smaller than or equal to 5 half-lives prior to enrollment, that may interfere, in the investigator's opinion, with the study results. * Subject has a history of any illness or condition which, in the investigator's opinion, may interfere with safe and optimal participation in the study. Healthy volunteers * Subject has a history of any illness or condition which may affect the normal somatosensory functionality. * Subject has eczema, scleroderma, psoriasis, dermatitis, or any other abnormality on the skin of the dominant hand and/or lower back which, in the investigator's opinion, might interfere with the study assessments. * Female who is pregnant or breast-feeding. * Simultaneous participation in another study which, in the investigator's opinion, might confound the results of the study. * Subject is unable to refrain from drinking alcohol 24 hours prior to each study visit, and/or consumes ≥ 3 alcoholic consumptions per day. * Subject is a regular user of cannabis, any illicit drugs and/or has a history of drug abuse. * Subject is unable to refrain from drinking caffeinated beverages (such as coffee, tea, cola,…) 24 hours prior to each study visit. * Subject has used concomitant drugs and/or treatments in a period smaller than or equal to 5 half-lives prior to enrollment, that may interfere, in the investigator's opinion, with the study results. * Subject has a history of any illness or condition which, in the investigator's opinion, may interfere with safe and optimal participation in the study.