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New therapy aims to help teens battling addiction and anxiety

NCT ID NCT01117753

Disease control Sponsor: Medical University of South Carolina Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new behavioral therapy called OPT-A for teenagers who have both substance use problems and mood or anxiety disorders. 140 teens aged 10-17 will receive either OPT-A or standard treatment. Researchers will track substance use and mental health for 18 months to see if the new therapy works better.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
OutPatient Treatment for Adolescents (OPT-A) - a behavioral therapy
What this could lead to
If successful, this could provide an effective treatment option for teens struggling with both substance use and mental health issues, improving their outcomes.
What could go wrong
This is a relatively small, early-stage trial (140 participants). The results may not apply to all teens, and the new therapy may not prove better than usual care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

140 people

The number who actually took part.

Start date

Jul 2009

Finished

Jun 2014

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

10 to 17 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 10 to 17 years of age * Residing with at least one adult caregiver who serves as a parent figure * In need of treatment for a Substance Abuse or Dependence Disorder * In need of treatment for an Axis I Mood Disorder and/or Anxiety Disorder Exclusion Criteria: * Pervasive Developmental Disorder * Active Psychotic Disorder * Severe or profound mental retardation

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Conditions

The condition(s) this trial relates to.

anxiety disorder depressive disorder mood disorder substance-related disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anxiety disorder Depressive disorder Substance-related disorders

Contacts and locations

Locations

  • Medical University of South Carolina, Department of Psychiatry & Behavioral Sciences, Family Services Research Center

    Charleston, South Carolina, 29425, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.