Fat tissue secrets in kidney disease revealed?
NCT ID NCT02902705
First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This completed study looked at fat tissue in 23 men with advanced chronic kidney disease (stage V) who were not on dialysis. Researchers compared their fat cells to those of healthy men to understand why kidney disease causes problems like weight loss and insulin resistance. Fat samples were taken during planned surgeries and analyzed for cell size and gene activity.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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23 people
The number who actually took part.
- Start date
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Sep 2009
- Finished
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Jul 2015
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Male participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: CKD (Chronic Kidney Disease) and non-CKD patients: * At least 18 years of age * Able and willing to provide informed consent * Male gender * Normal fasting glucose (less than 6 mmol/l ) * No evidence of significant concurrent illness * BMI \<30 kg/m2 * Non acidotic (bicarbonate \>20 mmol/L) * Normal coagulation profile CKD patients: • eGFR (estimated Glomerular Filtration Rate)\< 25 mL/min/m2 before the beginning of renal suppletion therapy Non-CKD patients: • eGFR \>50 mL/min/m2 Exclusion Criteria: * A known diagnosis of diabetes mellitus * enrolled in a other study that may confound results of this study. * Have been treated with: corticosteroids or insulin or oral diabetic medications within 8 days prior to study entry * Unwilling and/or not able to give written consent * Patient with active systemic bacterial, viral or fungal infections
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Service de Néphrologie, dialyse, hypertension artérielle - Pavillon P - Hôpital Edouard Herriot -
Lyon, 69003, France
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