Hidden air pockets in skull may reshape Eye's nerve pathway
NCT ID NCT07451080
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at 100 adults to see if a common anatomical variation—an air pocket in a small bone near the eye socket—changes the shape of the optic canal or the thickness of the nerve layer at the back of the eye. Using CT scans and eye imaging, researchers compared people with and without this air pocket. The goal was simply to understand the relationship, not to test a treatment.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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100 people
The number who actually took part.
- Started
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Aug 2025
- Finished
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Feb 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
This study population consists of adult patients aged 18 to 65 years who underwent both head and neck computed tomography (CT) imaging and optical coherence tomography (OCT) examinations at Elazığ Fethi Sekin City Hospital between August 2018 and July 2025. Patients will be retrospectively identified through the hospital electronic medical record and PACS archive systems. Participants will be categorized based on the presence or absence of anterior clinoid process (ACP) pneumatization on CT imaging.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 18 to 65 years. * Availability of head and neck computed tomography (CT) imaging in the hospital archive. * Availability of optical coherence tomography (OCT) examination records in the hospital archive. * CT and OCT examinations performed between August 2018 and July 2025. Exclusion Criteria: * Age \<18 years or \>65 years. History or evidence of diabetes mellitus. History or evidence of hypertension. Glaucoma. Any condition or diagnosis that may cause optic nerve pathology (e.g., optic neuritis, compressive optic neuropathy, optic atrophy, demyelinating disease affecting the optic nerve). Inadequate image quality or incomplete CT/OCT data preventing reliable measurements.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Fethi Sekin City Hospital
Elâzığ, Turkey (Türkiye)
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