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New hope for tough depression? drug trial targets Non-Responders

NCT ID NCT07284667

First seen Jan 04, 2026 · Last updated Jun 17, 2026 · Updated 25 times

Summary

This study tests a new medicine called ACP-211 in adults with major depression who haven't gotten better with standard antidepressants. About 153 people will receive either the drug or a placebo for 28 days. The main goal is to see if ACP-211 reduces depression symptoms more than a placebo.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Baylor College of Medicine

    RECRUITING

    Houston, Texas, 77030, United States

  • CenExel Hassman Research Institute, LLC

    ACTIVE_NOT_RECRUITING

    Marlton, New Jersey, 08053, United States

  • Clinical Neuroscience Solutions, Inc.

    RECRUITING

    Orlando, Florida, 32801, United States

  • Dynamed Clinical Research LP d/b/a DM Clinical Research

    ACTIVE_NOT_RECRUITING

    Houston, Texas, 77081, United States

  • Family Psychiatry of The Woodlands

    RECRUITING

    The Woodlands, Texas, 77381, United States

  • IPTB Clinical Research

    RECRUITING

    Tampa, Florida, 33629, United States

  • Inland Psychiatric Medical Group

    RECRUITING

    Chino, California, 91710, United States

  • Integrative Clinical Trials LLC

    RECRUITING

    Brooklyn, New York, 11229, United States

  • Kadima Neuropsychiatry Institute

    RECRUITING

    La Jolla, California, 92037, United States

  • Magnolia Clinical Research, LLC

    RECRUITING

    Cary, North Carolina, 27511, United States

  • Mountain View Clinical Research

    RECRUITING

    Denver, Colorado, 80209, United States

  • Neuro-Behavioral Clinical Research

    RECRUITING

    North Canton, Ohio, 44720, United States

  • Neuroscience Research Institute, Inc.

    RECRUITING

    West Palm Beach, Florida, 33407, United States

  • Olympus Clinical Research, LLC

    RECRUITING

    Katy, Texas, 77450, United States

  • PNS Clinical Research LLC dba ATP Clinical Research

    RECRUITING

    Orange, California, 92866, United States

  • Redbird Research LLC

    RECRUITING

    Las Vegas, Nevada, 89134, United States

  • Sandhill Research, LLC/DBA Accel Research Sites

    ACTIVE_NOT_RECRUITING

    Largo, Florida, 33777, United States

  • St. Charles Psychiatric Associates, Inc. dba Midwest Research Group

    RECRUITING

    Saint Charles, Missouri, 63304, United States

  • The Medici Medical Research

    RECRUITING

    Hollywood, Florida, 33021, United States

  • University of Alabama at Birmingham

    RECRUITING

    Birmingham, Alabama, 35294, United States

  • Vitalix Clinical, Inc.

    RECRUITING

    Worcester, Massachusetts, 01608, United States

Conditions

The condition(s) this trial relates to.

depressive disorder Depressive Disorder, Treatment-Resistant major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.