New hope for tough depression? drug trial targets Non-Responders

NCT ID NCT07284667

Recruiting now Symptom relief Sponsor: ACADIA Pharmaceuticals Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 07, 2026 · Updated 6 times

Summary

This study tests a new medicine called ACP-211 in adults with major depression who haven't gotten better with standard antidepressants. About 153 people will receive either the drug or a placebo for 28 days. The main goal is to see if ACP-211 reduces depression symptoms more than a placebo.

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Conditions

The condition(s) this trial relates to.

depressive disorder Depressive Disorder, Treatment-Resistant major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEPRESSIVE DISORDER, TREATMENT-RESISTANT MAJOR DEPRESSIVE DISORDER (MDD)

Contacts and locations

Locations

Adams Clinical, Inc.
RECRUITING

Watertown, Massachusetts, 02472, United States
Alivation Research, LLC
RECRUITING

Lincoln, Nebraska, 68526, United States
Baylor College of Medicine
RECRUITING

Houston, Texas, 77030, United States
Behavioral Research Specialists, LLC
RECRUITING

Glendale, California, 91107, United States
CenExel Hassman Research Institute, LLC
ACTIVE_NOT_RECRUITING

Marlton, New Jersey, 08053, United States
Clinical Neuroscience Solutions, Inc.
RECRUITING

Orlando, Florida, 32801, United States
Dynamed Clinical Research LP d/b/a DM Clinical Research
WITHDRAWN

Houston, Texas, 77081, United States
Family Psychiatry of The Woodlands
RECRUITING

The Woodlands, Texas, 77381, United States
IPTB Clinical Research
RECRUITING

Tampa, Florida, 33629, United States
Inland Psychiatric Medical Group
RECRUITING

Chino, California, 91710, United States
Integrative Clinical Trials LLC
RECRUITING

Brooklyn, New York, 11229, United States
Kadima Neuropsychiatry Institute
RECRUITING

La Jolla, California, 92037, United States
Magnolia Clinical Research, LLC
RECRUITING

Cary, North Carolina, 27511, United States
Mountain View Clinical Research
RECRUITING

Denver, Colorado, 80209, United States
Neuro-Behavioral Clinical Research
RECRUITING

North Canton, Ohio, 44720, United States
Neuroscience Research Institute, Inc.
RECRUITING

West Palm Beach, Florida, 33407, United States
New Access Research and Medical Services, Inc.
RECRUITING

Fort Myers, Florida, 33901, United States
Olympus Clinical Research, LLC
RECRUITING

Katy, Texas, 77450, United States
PNS Clinical Research LLC dba ATP Clinical Research
RECRUITING

Orange, California, 92866, United States
Precise Research Centers
RECRUITING

Flowood, Mississippi, 39232, United States
Redbird Research LLC
RECRUITING

Las Vegas, Nevada, 89134, United States
Sandhill Research, LLC/DBA Accel Research Sites
ACTIVE_NOT_RECRUITING

Largo, Florida, 33777, United States
St. Charles Psychiatric Associates, Inc. dba Midwest Research Group
RECRUITING

Saint Charles, Missouri, 63304, United States
The Medici Medical Research
RECRUITING

Hollywood, Florida, 33021, United States
University of Alabama at Birmingham
ACTIVE_NOT_RECRUITING

Birmingham, Alabama, 35294, United States
Vitalix Clinical, Inc.
RECRUITING

Worcester, Massachusetts, 01608, United States

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